Endocrine Abstracts

Introduction: Chronic endogenous hypercortisolism in Cushing’s syndrome imposes a great clinical burden of comorbidities, some of which might persist even after disease remission. Our aim was to analyze factors that predict long-term comorbidities after surgical remission of Cushing’s disease (CD).Subjects and methods: We retrospectively analyzed 37 patents (91.9% females) aged 39.5±13.9 years (10-70) with diagnosed CD, treated in our inst...

Introduction: Xanthomatous hypophysitis (XH) is characterized by inflammatory infiltration of the pituitary gland in which lipid laden macrophages predominate. It can be primary (3% of all primary hypophysitis) and secondary arising in the setting of other lesions: craniopharyngioma, Rathke’s cleft cyst (RCC), adenomas (with subclinical apoplexy). It is more common in women and younger people. The clinical presentation is similar to pituitary tumors and may prese...

IntroductionHematological neoplastic mass lesions of the sellar region are rare.Aim of the studyTo analyze a case series of patients with hematological malignancies affecting sellar region.Patients and methodsA retrospective study of 1166 patients with sellar lesions diagnosed at Department of Neuroendocrinology over the 16-year period (2005-2020).The demographics...

Background: Extended life expectancy and increase in neuroimaging availability, lead to increase in incidence of pituitary adenomas (PA) diagnosed after the age of 70. Recognition of PA in the elderly may be challenging and delayed due to symptoms overlapping with aging and comorbidities.Objective: To investigate character and presenting symptoms of PA in patients diagnosed after the age of 70.Methods: 105 patients (7.9%) with PA d...

Background: Increased life expectancy and wider availability of neuroimaging lead to increase in diagnosis of acromegaly in elderly patients, after the age of 70. Delay in diagnosis is attributable to milder symptomatology, higher prevalence of comorbidities and symptoms overlapping with normal aging process.Objective: To investigate clinical characteristics, presenting symptoms, comorbidities and treatment modalities of acromegaly in patients diagnosed ...

Introduction: Acromegaly is a rare chronic disease characterized by systemic comorbidity. As a chronic disease, which in most cases requires long-term treatment, it is often accompanied by musculoskeletal, metabolic, and cardiovascular diseases, as well as headaches, anxiety, and depression, which leads to impaired quality of life.Aim: Assessment of quality of life in patients with acromegaly compared to healthy controls.Materials ...